02Sep2018

How NASA’s Trying To Find Better Cancer Treatments In Space

Because of an astronaut, a blood cell experiment may deliver improvements on cancer-fighting treatments. There’s a lot of blood in space right now — to be exact, there are a lot of endothelial cells that come from blood vessels.

Astronauts are helping study these cells aboard the International Space Station (ISS) as part of the Angiex Cancer Therapy trials, which NASA astronaut Serena Auñón-Chancellor introduced in a new video published by NASA on Tuesday (Aug. 21).

An Expedition 56 crewmember, Auñón-Chancellor arrived to the space station earlier this summer. She’ll spend the next few months on the station, a space lab where crewmembers support and communicate with researchers here on Earth to run experiments. [Breathtaking Time-Lapse Video Shows Earth from International Space Station]

Why take a blood experiment into space? Sometimes, cells act differently in the weightless environment of orbiting spacecraft, called microgravity. And according to a NASA page on the research, endothelial cells housed within culture dishes (in vitro) in microgravity seem to perform as if they were in blood vessels within a living organism (in vivo) on Earth.

Astronauts at work facilitating experiments on the International Space Station. In the foreground, NASA astronaut Serena Auñón-Chancellor conducts research operations inside the Microgravity Science Glovebox (MSG) for the Angiex Cancer Therapy study. NASA astronaut Drew Feustel is seen in the background, working on the Microgravity Investigation of Cement Solidification (MICS) experiment.

Astronauts at work facilitating experiments on the International Space Station. In the foreground, NASA astronaut Serena Auñón-Chancellor conducts research operations inside the Microgravity Science Glovebox (MSG) for the Angiex Cancer Therapy study. NASA astronaut Drew Feustel is seen in the background, working on the Microgravity Investigation of Cement Solidification (MICS) experiment. Credit: NASA/Expedition 56 Crew

Because these orbiting cells perform more like they normally do inside the body, cancer researchers can more accurately test the cells for chemotherapy responses. Several cartridge-shaped containers on board the International Space Station currently host the cells as they undergo varying amounts of chemotherapy exposure. The study may lead to new testing models for Angiex researchers, too.

“The study may facilitate a cost-effective method that does not require animal testing,which may help develop safer and more-effective vascular-targeted drugs,” the project page reads.

In the video, Auñón-Chancellor said the flat endothelial containers feel “all nice and warm and comfortable,” because they are kept at body temperature aboard the space lab. “We’ve had them for almost two months now up here in ISS. We feed them. We give them nutrients … they are like miniature crewmembers living with us.” Adapted: Space

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